Career Development Program
Under the direction of Dr. Paige Tolbert, the Career Development Program serves to recruit new faculty in environmental health sciences into the Center and foster professional development of Center Members. Highlights of the Career Development Program include:
Facilitating new collaborations and entry of established scientists into environmental health research.
Promoting cross-training across all levels of faculty in emerging areas of environmental health sciences.
Fostering investigator growth by providing feedback through work-in-progress and grants-in-preparation presentations.
Formal mentoring program for junior faculty.
Understanding Human Diseases Through Metabolomics: Interactions Among the Genome, Proteome, Gut Microbiome and Nutrition
HERCULES Investigator: Donghai Liang Dates: February 3-8, 2019 Location: Ventura, CA Website: https://www.grc.org/metabolomics-and-human-health-conference/2019/...
HERCULES Investigator: Stefanie Sarnat In preparation for work on the Predictive Health Institute’s Center for Health Discovery and Well Being Cohort, e.g., Provide support for biological...
NIEHS Workshop: Statistical Approaches for Assessing Health Effects for Environmental Mixtures in Epidemiology Studies
Supported workshop participation for: Matt Strickland, RSPH EH Jenna Krall, RSPH BIOS Howard Chang, RSPH BIOS Jeffrey Switchenko, RSPH BIOS Sophia Banton, SOM Andrei Todor, SOM Dates: July 13-14,...
HERCULES Investigator: Rabin Tirouvanziam Dates: June 29-July 22, 2015 Location: San Francisco, CA Website: http://metabolomics2015.org/# ...
Career Development Highlights
Rabin Tirouvanziam, Department of Pediatrics
Year Two pilot recipient, Rabin Tirouvanziam, continues to be an excellent example of how the resources and support from the HERCULES Center has helped promote environmental health sciences research and created opportunities for researchers to expand their focus to include environmental factors. Tirouvanziam’s pilot project “The human airway ecosystem: metabolomics and trace element profiling to track complex exposures in chronic and acute disease” utilized the metabolomics and systems biology cores.
Before receiving his pilot award, Dr. Tirouvanziam had a well-established career in pulmonary research, immunology and metabolism. His most recent work had started to focus on using high-content platforms to interrogate immunometabolic processes. The HERCULES pilot award and access to the facility cores provided an additional seed to facilitate the expansion of his research to include environmental factors, high-resolution metabolomics and systems-based approaches. Beyond his pilot award, he has leveraged the use of career development resources to allow protected time for cross training to continue to enhance his knowledge of metabolomics.
Through his project, he was able to develop a pipeline for metabolomics and trace element profiling of airway fluid and initiate targeted analysis and data modeling efforts for disease-relevant analytes. Now that the pipeline is in place, data from this project has been expanded to include more samples from adults with chronic cystic fibrosis (CF) disease along with a group of infants with CF. Within only two years since his pilot award, he has successfully presented the metabolomics data at two major conferences and utilized the data to obtain a grant from the NIH Common Fund Metabolomics Resource along with an R01 from NHLBI. Additional R01 applications are currently underway along with multiple manuscripts describing the project findings.