Environment-Wide Association Studies (EWAS) provide an untargeted and comprehensive approach for considering environmental factors and their involvement in complex health/disease traits. EWAS techniques are analogous to GWAS approaches and as an extension, layering GWAS and EWAS approaches offer a strategy to identify specific complex traits with larger and more relevant impacts on disease.
An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus. Patel et al 2010
Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus. Patel et al 2013
Systematic evaluation of environmental and behavioural factors associated with all-cause mortality in the United States national health and nutrition examination survey. Patel et al 2013
An environmental wide association study (EWAS) approach to the metabolic syndrome. Lind et al 2013
Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank. Hall et al 2014
Development of exposome correlation globes to map out environment-wide associations. Patel, CP, Manrai, AK 2015