Redox biology: Interface of the exposome with the proteome, epigenome, and genome

Young-Mi Go, Dean Jones

Redox biology is a key component of understanding each individual’s exposome, accounting for how the body responds to environmental, dietary and behavioral risk factors of disease. Go and Jones call for redox biologists to assist in the development of concepts and strategies to sequence the exposome, proposing that databases with redox properties of biomolecules, common reaction rates and abundance measures of redox components may be necessary to truly take on these complex interactions. Redox biology offers a bridge across the exposome’s interface with the proteome, epigenome and genome, providing a means to sketch mechanisms occurring from varied exposures and distinct biological responses.

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